I work as a scientific consultant at ELKMO (registered CVR 43917897).
My clients include the Steinegger lab at SNU.
Before that I was a postdoc with Dr. Johannes Söding at MPIBPC, where I developed tools for the analysis of eukaryotic metagenomic data.
Before that, I did my PhD at TAU under the joint supervision of Prof. Tal Pupko and Prof. Itay Mayrose, focusing on statistical techniques in molecular evolution.
Postdoc in Computational Biology, 2021
Max-Planck Institute for Biophysical Chemistry
PhD in Molecular Evolution, 2018
Tel Aviv University
MSc in Theoretical and Mathematical Biology, 2014
Tel Aviv University
BSc in Computer Science, 2011
Tel Aviv University
BSc in Biology, 2008
Tel Aviv University
MetaEuk is a modular toolkit designed for large-scale gene discovery and annotation in eukaryotic metagenomic contigs. It combines fast and sensitive homology search capabilities with a dynamic programming procedure to recover optimal exons sets. It reduces redundancies in multiple discoveries of the same gene and resolves conflicting gene predictions.
TraitRateProp is a method for testing whether the rate of sequence evolution of a protein or genomic region is associated with changes in a binary phenotypic trait. It detects specific sequence sites whose evolutionary rate is most affected following trait transitions, suggesting a shift in functional/structural constraints.
SpartaABC is an Approximate Bayesian Computation (ABC) reject algorithm to infer insertion and deletion (indel) parameters from sequence data. SpartaABC infers the indel-to-substitution rate ratio (IR), the shape parameter (A) of the power law distribution controlling the indel length, and the root length parameter (RL).
SimBa-SAl is a simulation-based approach for statistical alignment inference. The SimBa-SAl simulator implements a stochastic evolutionary model of indel formation and generates a long true alignment. It tabulates the probabilities of chop-associated segments (Miklos et al. 2004) based on their frequencies in simulation. The SimBa-SAl inference program takes as input such tabulated chop probabilities and uses them for various statistical alignment computations.